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Alternative name
DKFZp313J1712, FP793, RN, RNU2AF1, U2AF1, U2AF35, U2AFBP antibody
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Catalog
A009137
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenU2 small nuclear RNA auxiliary factor 1
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A009137(U2AF35 antibody) at dilution of 1:100
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Western BlotCOLO 320 cells were subjected to SDS PAGE followed by western blot with A009137(U2AF35 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000;IHC:1:20-1:200
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Product Description specificalU2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
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Gene nameU2AF1
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locationNucleus,Spliceosome
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Uniprot IDQ01081
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Calculated M.W.28kDa,0beserved 40kDa
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Observed M.W.35kd
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