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Alternative name
FLJ10128, KIAA1561, NUCLING, UACA antibody
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Catalog
A009140
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenuveal autoantigen with coiled-coil domains and ankyrin repeats
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A009140( UACA Antibody) at dilution of 1:2000
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Recommended dilutionWB : 1:1000-1:10000;IF:1:20-1:200
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Product Description specificalRegulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). _x000D_Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation (By similarity).
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Gene nameUACA
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locationCytoplasm,Cytoskeleton,Nucleus
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Uniprot IDQ9BZF9
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Calculated M.W.163kDa
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Observed M.W.163 kDa
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