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Alternative name
BMP2A antibody
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Catalog
A000917
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat,Pig
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenbone morphogenetic protein 2
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IHCImmunohistochemistry of paraffin-embedded human small intestine tissue slide using; A000917 (BMP2 Antibody) at dilution of 1:50 A000917
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A000917(BMP2 antibody) at dilution of 1:100
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Recommended dilutionWB: 1:500-1: 5000;IHC: 1:20-1:200;IF: 1:50-1:500
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Product Description specificalInduces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
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Gene nameBMP2
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Uniprot IDP12643
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Observed M.W.45 kDa
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