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Alternative name
Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1 antibody
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Catalog
A009218
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IP
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PurificationImmunogen affinity purified
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Immunogenubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
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Western BlotA549 cells were subjected to SDS PAGE followed by western blot with A009218(UCHL1 antibody) at dilution of 1:400
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Recommended dilutionWB : 1:500-1:5000;IF：N/A;IP:1:1000-1:10000
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Product Description specificalUCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890).
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Gene nameUCHL1
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locationCytoplasm,Endoplasmic reticulum,Membrane
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Uniprot IDP09936
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Calculated M.W.26kDa
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Observed M.W.27 kDa
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