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Alternative name
UB fusion protein 1, UFD1, UFD1L antibody
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Catalog
A009233
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogenubiquitin fusion degradation 1 like (yeast)
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IHCImmunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using A009233( UFD1L Antibody) at dilution of 1:50
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Western Blotmouse thymus tissue were subjected to SDS PAGE followed by western blot with A009233( UFD1L Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000;IHC:1：20-1:200;IP:1：50O-1:5000;IF:1：10-1:100
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Product Description specificalEssential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
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Gene nameUFD1L
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locationCytoplasm,Nucleus
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Uniprot IDQ92890
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Calculated M.W.35kDa
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Observed M.W.35 kDa
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