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Alternative name
KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A (C. elegans), UNC13A antibody
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Catalog
A009255
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenunc-13 homolog A (C. elegans)
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Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A009255(UNC13A antibody) at dilution of 1:300
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Recommended dilutionWB : 1:500-1:5000;IP:1：200-1：2000
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Product Description specificalUNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.
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Gene nameUNC13A
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locationCell junction,Cell membrane,Cytoplasm,Membrane,Synapse
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Uniprot IDQ9UPW8
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Calculated M.W.193kDa
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Observed M.W.193-210 kDa
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