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Alternative name
Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14 antibody
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Catalog
A009310
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,FC
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PurificationImmunogen affinity purified
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Immunogenubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
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Western Blotmouse kidney tissue were subjected to SDS PAGE followed by western blot with A009310(USP14 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:500-1:5000;IP:1:500-1:5000;IF:1:10-1:100
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Product Description specificalProteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
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Gene nameUSP14
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Uniprot IDP54578
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Calculated M.W.52kDa,Observed 52kDa,60kDa
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Observed M.W.52 kDa,60 kDa
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