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Alternative name
Deubiquitinating enzyme 49, Ubiquitin thiolesterase 49, USP49 antibody
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Catalog
A009338
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenubiquitin specific peptidase 49
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IHCImmunohistochemistry of paraffin-embedded human stomach using A009338(USP49 antibody) at dilution of 1:50
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A009338(USP49 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000;IHC:1：20-1：200
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Product Description specificalSpecifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
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Gene nameUSP49
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locationNucleus
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Uniprot IDQ70CQ1
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Calculated M.W.73kDa，Observed 55kDa，73kDa
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Observed M.W.79-85 kDa
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