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Alternative name
ArPIKfyve, FLJ10305, FLJ36622, FLJ46582, Protein VAC14 homolog, Tax1 binding protein 2, TAX1BP2, TRX, VAC14, Vac14 homolog (S. cerevisiae) antibody
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Catalog
A009356
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenVac14 homolog (S. cerevisiae)
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IHCImmunohistochemistry of paraffin-embedded human skin using A009356(VAC14 antibody) at dilution of 1:100
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Western Blothuman spleen tissue were subjected to SDS PAGE followed by western blot with A009356(VAC14 antibody) at dilution of 1:500
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Recommended dilutionWB :1:500-1:5000;IP:1:200-1:2000；IHC:1:20-1:200
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Product Description specificalThe PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
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Gene nameVAC14
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locationEndoplasmic reticulum,Endosome,Membrane,Microsome
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Uniprot IDQ08AM6
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Calculated M.W.88kDa，Observed 88kDa，65kDa
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Observed M.W.88 kDa,65 kDa
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