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Alternative name
33 kDa VAMP associated protein, hVAP 33, VAMP A, VAMP associated protein A, VAP 33, VAP A, VAP33, VAPA antibody
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Catalog
A009369
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenVAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A009369(VAPA antibody) at dilution of 1:100
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Western Blothuman kidney tissue were subjected to SDS PAGE followed by western blot with A009369(VAPA antibody) at dilution of 1:500
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Recommended dilutionWB :1:500-1:5000;IHC:1:50-1:200；IF:1:10-1:100;IP:1:500-1:5000
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Product Description specificalBinds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204). With OSBPL3, may regulate ER morphology (PubMed:16143324). May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470).
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Gene nameVAPA
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locationCell junction,Cell membrane,Endoplasmic reticulum,Membrane,Nucleus,Tight junction
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Uniprot IDQ9P0L0
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Calculated M.W.33kDa
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Observed M.W.33 kDa
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