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Alternative name
L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF antibody
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Catalog
A009391
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,IF,IP,WB
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PurificationImmunogen affinity purified
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Immunogenvascular endothelial growth factor A
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IHCImmunohistochemistry of paraffin-embedded human lung cancer tissue slide using A009391( VEGFA Antibody) at dilution of 1:200
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Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A009391(VEGFA antibody) at dilution of 1:800
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Recommended dilutionWB :1:200-1:2000;IP:1:200-1:2000;IF:1:10-1:100;IHC:1:50-1:500
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Product Description specificalVEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010 ). This antibody can recognize all the isoforms of VEFGA.
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Gene nameVEGFA
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locationSecreted
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Uniprot IDP15692
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Calculated M.W.27kDa
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Observed M.W.23-27 kDa,45 kDa
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