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Alternative name
1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN antibody
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Catalog
A009412
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat,Zebrafish
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Applications Tested/SuitableELISA,IHC,WB,IP
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PurificationImmunogen affinity purified
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Immunogennicotinamide phosphoribosyltransferase
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IHCImmunohistochemistry of paraffin-embedded human ovary tumor using A009412(NAMPT antibody) at dilution of 1:50
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Western Blotmouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with A009412( NAMPT Antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200;IP:1:500-1:5000
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Product Description specificalNicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
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locationCytoplasm,Nucleus,Secreted
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Uniprot IDP43490
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Calculated M.W.55kDa
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