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Alternative name
DERP9, EAP20, ESCRT II complex subunit VPS25, FAP20, hVps25, VPS25 antibody
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Catalog
A009431
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenvacuolar protein sorting 25 homolog (S. cerevisiae)
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A009431(VPS25 antibody) at dilution of 1:50
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A009431(VPS25 antibody) at dilution of 1:500
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Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200
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Product Description specificalComponent of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
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Gene nameVPS25
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Uniprot IDQ9BRG1
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Calculated M.W.21kDa
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Observed M.W.21 kDa
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