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Alternative name
FLJ10979, HCCS1, hVps53L, pp13624, VPS53 antibody
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Catalog
A009448
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenvacuolar protein sorting 53 homolog (S. cerevisiae)
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Western Blothuman liver tissue were subjected to SDS PAGE followed by western blot with A009448(VPS53 antibody) at dilution of 1:300
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Recommended dilutionWB :1:500-1:5000；IP:1:200-1:2000
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Product Description specificalActs as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
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Gene nameVPS53
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Uniprot IDQ5VIR6
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Calculated M.W.96kDa
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Observed M.W.95-97 kDa
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