-
Alternative name
FLJ32099, KIAA0804, VPS8 antibody
-
Catalog
A009451
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IF，IP
-
PurificationImmunogen affinity purified
-
Immunogenvacuolar protein sorting 8 homolog (S. cerevisiae)
-
Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A009451(VPS8 antibody) at dilution of 1:500
-
Recommended dilutionWB :1:500-1:5000；IP:1:200-1:2000;IF:1:10-1:100
-
Product Description specificalPlays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290).
-
Gene nameVPS8
-
locationEndosome
-
Uniprot IDQ8N3P4
-
Calculated M.W.151kDa
-
Observed M.W.151 kDa
-