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Alternative name
WDR5, BIG3, BMP2 induced 3 kb gene protein, WD repeat containing protein 5, SWD3 antibody
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Catalog
A009497
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenWD repeat domain 5
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IHCImmunohistochemistry of paraffin-embedded human brain using A009497(WDR5 antibody) at dilution of 1:100
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Western BlotNIH/3T3 cells were subjected to SDS PAGE followed by western blot with A009497(WDR5 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000;IHC:1:20-1:200
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Product Description specificalContributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
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Gene nameWDR5
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locationNucleus
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Uniprot IDP61964
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Calculated M.W.36kDa,observed 42kDa,36kDa
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Observed M.W.36kd
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