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Alternative name
FLJ10385, TCAB1, WDR79, WRAP53 antibody
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Catalog
A009523
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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ImmunogenWD repeat containing, antisense to TP53
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IHCImmunohistochemistry of paraffin-embedded human testis using A009523(WRAP53 antibody) at dilution of 1:100
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Western Blothuman kidney tissue were subjected to SDS PAGE followed by western blot with A009523(WRAP53 antibody) at dilution of 1:300
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:1000
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Product Description specificalEssential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post- transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
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Gene nameWRAP53
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locationCytoplasm,Nucleus
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Uniprot IDQ9BUR4
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Calculated M.W.59kDa,Observed 72kDa
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Observed M.W.72-75 kDa
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