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Alternative name
GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT 2, WT1, WT33 antibody
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Catalog
A009528
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IP
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PurificationImmunogen affinity purified
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ImmunogenWilms tumor 1
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Western Blothuman kidney tissue were subjected to SDS PAGE followed by western blot with A009528(WT1 antibody) at dilution of 1:300
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Recommended dilutionWB:1:500-1:5000;IP:1:500-1:5000
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Product Description specificalTranscription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
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Gene nameWT1
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locationCytoplasm,Nucleus
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Uniprot IDP19544
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Calculated M.W.49kDa,Observed 33kDa,55kDa
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Observed M.W.52-55kd
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