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Alternative name
D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1, WWOX antibody
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Catalog
A009533
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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ImmunogenWW domain containing oxidoreductase
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Western Blotmouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with A009533(WWOX antibody) at dilution of 1:300
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Recommended dilutionWB:1:500-1:5000;IP:1:200-1:2000
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Product Description specificalPutative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
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Gene nameWWOX
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locationCytoplasm,Golgi apparatus,Mitochondrion,Nucleus
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Uniprot IDQ9NZC7
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Calculated M.W.47kDa
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Observed M.W.46 kDa
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