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Alternative name
COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC antibody
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Catalog
A009547
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IP
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PurificationImmunogen affinity purified
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Immunogenexcision repair cross-complementing rodent repair deficiency, complementation group 5
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A009547(ERCC5 antibody) at dilution of 1:500
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Recommended dilutionWB:1:200-1:2000;IF:1:20-1:200;IP:1:200-1:2000
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Product Description specificalThe human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair (NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].
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Gene nameERCC5
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locationNucleus
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Uniprot IDP28715
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Calculated M.W.133kDa,Observed 200kDa
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Observed M.W.200 kDa
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