-
Alternative name
DNA repair protein XRCC4, XRCC4 antibody
-
Catalog
A009554
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IP
-
PurificationImmunogen affinity purified
-
ImmunogenX-ray repair complementing defective repair in Chinese hamster cells 4
-
IHCImmunohistochemistry of paraffin-embedded human breast cancer using A009554(XRCC4 antibody) at dilution of 1:100
-
Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A009554(XRCC4 antibody) at dilution of 1:1000
-
Recommended dilutionWB:1:1000-1:10000;IHC:1:20-1:200;IP:1:200-1:2000
-
Product Description specificalInvolved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
-
Gene nameXRCC4
-
locationNucleus
-
Uniprot IDQ13426
-
Calculated M.W.38kDa,Observed 55kDa
-
Observed M.W.55 kDa
-