-
Alternative name
DKFZp451J1719, DUBA 8, DUBA8, HIN 7, HIN7, HIV 1 induced protease 7, HsHIN7, OTUD2, PRO0907, Ubiquitin thioesterase OTU1, YOD1 antibody
-
Catalog
A009567
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB
-
PurificationImmunogen affinity purified
-
ImmunogenYOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
-
Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A009567( YOD1 Antibody) at dilution of 1:1000
-
Recommended dilutionWB:1:500-1:5000
-
Product Description specificalHydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
-
Gene nameYOD1
-
Uniprot IDQ5VVQ6
-
Calculated M.W.38kDa
-
Observed M.W.38 kDa
-