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Alternative name
14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB antibody
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Catalog
A009575
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC
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PurificationImmunogen affinity purified
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Immunogentyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
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IHCImmunohistochemical of paraffin-embedded human colon cancer using A009575(YWHAB antibody) at dilution of 1:50
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Recommended dilutionIHC:1:20-1:200
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Product Description specificalAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
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Gene nameYWHAB
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locationCytoplasm
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Uniprot IDP31946
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Calculated M.W.28kDa
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