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Alternative name
FLJ14840, MPFYVE, ZFYVE19 antibody
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Catalog
A009629
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenzinc finger, FYVE domain containing 19
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IHCImmunohistochemistry of paraffin-embedded human heart slide using A009629( ZFYVE19 Antibody) at dilution of 1:50
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A009629(ZFYVE19 antibody) at dilution of 1:2000
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Recommended dilutionWB : 1:1000-1:10000;IHC:1:20-1:200
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Product Description specificalKey regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
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Gene nameZFYVE19
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locationCytoplasm,Cytoskeleton
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Uniprot IDQ96K21
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Calculated M.W.52kDa
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Observed M.W.52 kDa
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