-
Alternative name
FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH antibody
-
Catalog
A009761
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
ImmunogenZwilch, kinetochore associated, homolog (Drosophila)
-
IHCImmunohistochemistry of paraffin-embedded human colon cancer tissue slide using A009761( ZWILCH Antibody) at dilution of 1:50
-
Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A009761( ZWILCH Antibody) at dilution of 1:500
-
Recommended dilutionWB:1:200-1:2000;IHC:1:20-1:200
-
Product Description specificalEssential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
-
Gene nameZWILCH
-
locationCentromere,Chromosome,Kinetochore
-
Uniprot IDQ9H900
-
Calculated M.W.67kDa
-
Observed M.W.~60 kDa
-