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Human IFNL2 ELISA Kit

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  • Alternative name

    Human IFN-lambda-2 ELISA Kit;Human cytokine Zcyto20 ELISA Kit;Human interleukin-28A ELISA Kit;Human IL-28A ELISA Kit;Human IL28A ELISA Kit;Human ZCYTO20 ELISA Kit;Human interferon lambda 2 ELISA Kit;Human interferon lambda-2 ELISA Kit;Human interleukin 28A (interferon, lambda 2) ELISA Kit;
  • Catalog
    E019453
  • species
    Human
  • GeneIFNL2
  • SpecificityNatural and recombinant human IL-28A
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman IFNL2 ELISA Kit allows for the in vitro quantitative determination of IFNL2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the assay: human IL-28A ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for IL-28A has been precoated onto 96-well plates. Standards(NSO, V26-V200) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for IL-28A is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human IL-28A amount of sample captured in plate. Background: Interferon lambda-2, also called IFNL2 or IL28A is a class II cytokine receptor ligand related to type I interferons. This gene is mapped to 19q13.2. This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster. It up-regulates MHC class I antigen expression. It also displays antitumor activity. The ligand/receptor complex seems to signal through the Jak-STAT pathway. This gene seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. It seems play a significant role in the antiviral immune defense in the intestinal epithelium.
  • Human Interferon lambda-2 Protein information
  • Uniprot ID IFNL2_HUMAN
  • Uniprot AC Q8IZJ0; Q45KQ8; Q6VN55; Q8IWL7;
  • UniGene Hs.567792;
  • GeneID 282616
  • KEGG hsa:282616;
  • Human Interferon lambda-2 Protein SEQUENCE

  • SEQUENCE 200 AA; 22288 MW; DFC7B49F31BF488E CRC64;

    MKLDMTGDCT PVLVLMAAVL TVTGAVPVAR LHGALPDARG CHIAQFKSLS

    PQELQAFKRA KDALEESLLL KDCRCHSRLF PRTWDLRQLQ VRERPMALEA

    ELALTLKVLE ATADTDPALV DVLDQPLHTL HHILSQFRAC IQPQPTAGPR

    TRGRLHHWLY RLQEAPKKES PGCLEASVTF NLFRLLTRDL NCVASGDLCV

  • UCSC uc002oku.2; human.;



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