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Alternative name
Human clara cell phospholipid-binding protein ELISA Kit;Human CCPBP ELISA Kit;Human clara cells 10 kDa secretory protein ELISA Kit;Human CC10 ELISA Kit;Human secretoglobin family 1A member 1 ELISA Kit;Human urinary protein 1 ELISA Kit;Human UP-1 ELISA Kit;Human UP1 ELISA Kit;Human urine protein 1 ELISA Kit;Human CCSP ELISA Kit;Human UGB ELISA Kit;Human CC16 ELISA Kit;Human uteroglobin ELISA Kit;Human blastokinin ELISA Kit;Human secretoglobin, family 1A, member 1 (uteroglobin) ELISA Kit;
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Catalog
E034314
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species
Human
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GeneSCGB1A1
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SpecificityNatural and recombinant human SCGB1A1
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SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
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Sensitivity< 10pg/ml
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Intended UseHuman SCGB1A1 ELISA Kit allows for the in vitro quantitative determination of SCGB1A1 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
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StorageStore the whole ELISA kit at 4℃
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Product Description
specificalPrinciple of the assay: human SCGB1A1 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for SCGB1A1 has been precoated onto 96-well plates. Standards(E.coli, E22-N91) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for SCGB1A1 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human SCGB1A1 amount of sample captured in plate.
Background: SCGB1A1(secretoglobin family 1A member 1) also known as Uteroglobin is a protein that in humans is encoded by the SCGB1A1 gene. SCGB1A1 is the founding member of the secretoglobin family of small, secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is specifically expressed in Clara cells in the lungs. Numerous studies demonstrated that UG is a multifunctional protein with antiinflammatory/ immunomodulatory properties. It inhibits soluble phospholipase A(2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its antiinflammatory activities, UG manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities.
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Human Uteroglobin Protein information
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Uniprot ID
UTER_HUMAN
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Uniprot AC
P11684; B2R5F2; Q6FHH3; Q9UCM2; Q9UCM4;
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UniGene
Hs.523732;
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GeneID
7356
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KEGG
hsa:7356;
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Human Uteroglobin Protein SEQUENCE
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SEQUENCE 91 AA; 9994 MW; FE65ACA678F12ABD CRC64;
MKLAVTLTLV TLALCCSSAS AEICPSFQRV IETLLMDTPS SYEAAMELFS
PDQDMREAGA
QLKKLVDTLP QKPRESIIKL MEKIAQSSLC N
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UCSC
uc001ntj.4; human.;
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