-
Alternative name
Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase antibody
-
Catalog
A001327
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF,IP
-
PurificationImmunogen affinity purified
-
Immunogencystathionine-beta-synthase
-
IHCImmunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using A001327( CBS Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
-
Western Blotmouse kidney tissue were subjected to SDS PAGE followed by western blot with A001327(CBS antibody) at dilution of 1:500
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalHydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L- homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
-
Gene nameCBS
-
Uniprot IDP35520
-
Observed M.W.61 kDa
-