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Alternative name
CD209L, CD209L1, CD299 antibody
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Catalog
A001757
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,IHC,WB
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PurificationImmunogen affinity purified
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ImmunogenC-type lectin domain family 4, member M
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IHCImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using A001757( CLEC4M Antibody) at dilution of 1:50
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Western BlotTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with A001757( CLEC4M Antibody) at dilution of 1:3000
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalProbable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. _x000D_(Microbial infection) Acts as an attachment receptor for ebola virus (PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus (PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1 (PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E (PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5 (PubMed:12433371). Acts as an attachment receptor for influenzavirus (PubMed:21191006). Acts as an attachment receptor for SARS coronavirus (PubMed:15479853). Acts as an attachment receptor for west-nile virus (PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus (PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein (PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule (PubMed:21203928).
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Gene nameCLEC4M
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Uniprot IDQ9H2X3
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