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Alternative name
ACAN, AGC1, AGCAN, aggrecan, CSPG1, CSPGCP, MSK16, SEDK antibody
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Catalog
A000213
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenaggrecan
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IHCImmunohistochemistry of paraffin-embedded human lung tissue slide using A000213( ACAN Antibody) at dilution of 1:400
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Western BlotROS1728 cells were subjected to SDS PAGE followed by western blot with A000213( ACAN Antibody) at dilution of 1:600
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Recommended dilutionWB :1:200-1:2000;IHC:1:20-1:200
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Product Description specificalAggrecan (ACAN), also named as CSPCP, AGC1 and MSK16, belongs to the aggrecan/versican proteoglycan family (also including versican, brevican and neurocan). It is a major component of extracellular matrix of cartilagenous tissues. A major function of aggrecan is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. This polyclonal antibody raised against 1-298aa of human aggrecan reveals a band of 70 kDa, which is consistent with the molecular weight of degradation product generated by proteolysis at the aggrecanase site (PMID: 7852317; 9337874).
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Gene nameACAN
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locationExtracellular matrix,Secreted
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Uniprot IDP16112
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Calculated M.W.250kDa,observed 70kDa
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Observed M.W.70 kDa
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