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Alternative name
FAM31A , KIAA1608 antibody
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Catalog
A002332
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IF
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PurificationImmunogen affinity purified
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ImmunogenDENN/MADD domain containing 1A
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalGuanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P (By similarity).
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Gene nameDENND1A
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Uniprot IDQ8TEH3
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Observed M.W.111 kDa, 64 kDa
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