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Alternative name
EIF2A antibody
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Catalog
A002699
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,FC,IP
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PurificationImmunogen affinity purified
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Immunogeneukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A002699(EIF2S1 antibody) at dilution of 1:50
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Western Blothuman stomach tissue were subjected to SDS PAGE followed by western blot with A002699(EIF2S1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalFunctions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
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Gene nameEIF2S1
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Uniprot IDP05198
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Observed M.W.36 kDa
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