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Alternative name
ABCE1, RLI, RNase L inhibitor, RNASEL1, OABP antibody
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Catalog
A000039
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenATP-binding cassette, sub-family E (OABP), member 1
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IHCImmunohistochemistry of paraffin-embedded human ovary tumor using A000039(ABCE1 antibody) at dilution of 1:50
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Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A000039(ABCE1 antibody) at dilution of 1:1500
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Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200
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Product Description specificalAntagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
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Gene nameABCE1
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locationCytoplasm,Mitochondrion
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Uniprot IDP61221
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Calculated M.W.67kDa
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Observed M.W.67kd
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