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Alternative name
Antithrombin, Antithrombin III, AT3, ATIII, HEPARIN COFACTOR I, Serpin C1, SERPINC1 antibody
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Catalog
A000448
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenserpin peptidase inhibitor, clade C (antithrombin), member 1
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Western Blothuman blood tissue were subjected to SDS PAGE followed by western blot with A000448(SERPINC1 antibody) at dilution of 1:300
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Recommended dilutionWB :1:200-1:1000;IF:1:50-1:500
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Product Description specificalSERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
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Gene nameSERPINC1
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locationSecreted
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Uniprot IDP01008
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Calculated M.W.53kDa
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Observed M.W.53 kDa
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