-
Alternative name
KIAA0864, MRIP, RHOIP3 antibody
-
Catalog
A005296
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF,IP
-
PurificationImmunogen affinity purified
-
Immunogenmyosin phosphatase Rho interacting protein
-
IHCImmunohistochemistry of paraffin-embedded human ovary using A005296(MPRIP antibody) at dilution of 1:100
-
Western BlotSH-SY5Y cells were subjected to SDS PAGE followed by western blot with A005296(MPRIP antibody) at dilution of 1:800
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalTargets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells.
-
Gene nameMPRIP
-
Uniprot IDQ6WCQ1
-
Observed M.W.116-140 kDa
-