-
Alternative name
ARF1GAP antibody
-
Catalog
A000536
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IP
-
PurificationImmunogen affinity purified
-
ImmunogenADP-ribosylation factor GTPase activating protein 1
-
IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A000536(ARFGAP1 antibody) at dilution of 1:100
-
Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A000536(ARFGAP1 antibody) at dilution of 1:400
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalGTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).
-
Gene nameARFGAP1
-
Uniprot IDQ8N6T3
-
Observed M.W.46 kDa, 50 kDa
-