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Alternative name
EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3 antibody
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Catalog
A006302
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenpaternally expressed 10
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A006302(PEG10 antibody) at dilution of 1:100
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A006302(PEG10 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalPrevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).
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Gene namePEG10
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Uniprot IDQ86TG7
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Observed M.W.50 kDa,100 kDa
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