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Alternative name
RGSZ2 antibody
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Catalog
A007268
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenregulator of G-protein signaling 17
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IHCImmunohistochemistry of paraffin-embedded human testis slide using A007268( RGS17 Antibody) at dilution of 1:50
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Western Blotmouse lung tissue were subjected to SDS PAGE followed by western blot with A007268(RGS17 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalRegulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
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Gene nameRGS17
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Uniprot IDQ9UGC6
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Observed M.W.27 kDa
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