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Alternative name
CGI 97, FLJ10917, SBDS, SDS, SWDS antibody
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Catalog
A007617
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenShwachman-Bodian-Diamond syndrome
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IHCImmunohistochemistry of paraffin-embedded human pancreas using A007617(SBDS antibody) at dilution of 1:50
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Western BlotHL-60 cells were subjected to SDS PAGE followed by western blot with A007617(SBDS antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalRequired for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP- dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
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Gene nameSBDS
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Uniprot IDQ9Y3A5
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Observed M.W.29 kDa
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