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Alternative name
Gene symbol ACO2 Synonyms ACO2, Aconitase, aconitase 2, aconitase 2, mitochondrial, ACONM, Citrate hydro lyase antibody
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Catalog
A000088
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenaconitase 2, mitochondrial
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IHCImmunohistochemistry of paraffin-embedded human lung cancer using A000088(ACO2 antibody) at dilution of 1:50
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Western Blothuman skeletal muscle tissue were subjected to SDS PAGE followed by western blot with A000088(ACO2 antibody) at dilution of 1:400
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Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200
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Product Description specificalACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration (ICRD).
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Gene nameACO2
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locationMitochondrion
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Uniprot IDQ99798?
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Calculated M.W.85kDa
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Observed M.W.85 kDa
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