As the baby develops, the decrease in the number of cells that connect neurons in the brain is thought to play a role in autism spectrum disorders.
Now, according to a study, these are known as the number of microglia and the changes in behavior in boys and girls, a finding that helps explain why there are a lot of boy was diagnosed with autism and related disorders.
The nerve geneticist at the university of California San Francisco, Donna Werling and colleagues found that a few months before birth, the genes associated with small cutin of nerve cells in the male brain than in the female brain more active.
"This shows that there are some very different areas of brain development in men and women."
She said.
The study, presented May 13 at the international autism research conference in San Francisco, California, is still in its infancy.
So far, little is known about how the small keratinous neurogenesis affects brain development.
But the study by Werling's team "is one of those things that will make you say, 'wow, this is really interesting, we should take it seriously.'"
"Said Kevin Pelphrey, a neuroscientist at the Yale school of medicine in new haven, Connecticut.
Men are two to five times more likely to develop autism than women.
The disease, which is still not known, is widely believed to have a lower diagnosis rate among women, and psychiatrists agree that there is a large gap between male and female cases.
It shows that there are biological differences in gender.
Werling began to study why men have higher rates of autism than women.
She and her colleagues examined how gene expression in male and female brain tissue changes.
Their initial prediction was that genes associated with autism were highly expressed in men.
But the team did not find a distinct pattern of autism gene expression that distinguishes men from women.
However, genes that cause glial nerve development or cell activation are more active in men.
Next, she and her colleagues grouped the brain samples based on age, and found that the glial gene expression between men and women was the most significant in the months before birth.
Some of her colleagues to be involved in a study published last year in nature, the study showed that microglial nerve related genes in the brains of people suffering from autism samples is a higher level than unaffected.
Overall, these results led Werling to believe that the higher levels of microglial nerves in the body during the birth of baby boys made them more sensitive to the genes associated with autism.
Another possibility, she said, was that the tiny glial nerve was less active and allowed them to be less affected by those genes.
prev:The things you and the mice did in those years(2017-07-20)
next:Cell freeze, recovery and cell count survival test(2017-07-21)