What is the Asprosin?


2017-08-15 20:03:24 GMT+0800

Neonatal premature aging disease (NPS, NeonatalProgeroidSyndrome) is a rare genetic disorder that is characterized by congenital part of fat metabolism disorders, mainly affecting the face and limbs.
Researchers conducted whole-genome sequencing and exon group, found that patients with NPS FBN1 (fibrilin 1, fibrillar protein) gene coding, pFBN1 fibrillar protein) before (profibrillin, will be cut to a, resulting in a defect pFBN1 C end, and the lack of this period was named asprosin.


Asprosin exists in the human plasma at the nanomole level. Compared with NPS, Asprosin in NPS is at a lower concentration level.
In the process of the research of the rare genetic disorders, have won a may affect hundreds of millions of new findings in patients with type 2 diabetes, because high blood sugar and insulin/obesity diabetes show asprosin levels higher than normal.


Research on asprosin and diabetes, there are many excellent literatures available for more researchers.


1.In February 2016 in "Cell" Asprosin, a fasting - induced glucogenic protein hormone.


2.Asprosin-new hormone involved in hepatic release in the April 2016 Nature Reviews Endocrinology.


3.In April 2016 Nature Reviews Drug Discovery "will be fat - secreted in the hormone regulates glucose homeostasis


4.In April 2016, in "Nature" New hormone regulates glucose.


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