On April 21, 2016, famous magazine "Cell", published in a paper entitled: "Asprosin, a Fasting - Induced Glucogenic Protein Hormone." research articles, the authors Chase Romere and others discovered a new regulating liver glucose released into the blood circulation, improve the blood glucose concentration of Protein Hormone, and name it: Asprosin.
Its adjustment mechanism is shown below:
Asprosin, in fact, is a two exons FBN1 gene encoding 140 amino acid composition of protein hormone, which is derived from the Profibrillin cracking a peptide fragments of protein C end, through the experiment, due to the modification after translation role in mammals, molecular weight of the hormone close to 30 kd, due to the pathogenesis of type 2 diabetes is associated with high fasting glucose, and accompanied by insulin resistance, thus about Asprosin in-depth study on the control and treatment of type 2 diabetes and drug development to bring a good prospect.
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