Did you distinguish between apoptosis and necrosis?


2017-09-12 22:06:02 GMT+0800

Many experiments friend said I do not know how to distinguish between apoptosis and necrosis, cell apoptosis and necrosis are actually two different forms of cell apoptosis, according to cell death in the differences in morphology, biochemistry and molecular biology, to distinguish between them.


conception
Cell apoptosis is to point to in order to maintain stable internal environment, autonomy, the differentiation of cell death controlled by the gene, he involves a series of activation, expression and regulation of gene function, has physiological and selective.


Physiological meaning
Apoptosis of embryonic development and morphogenesis, organization of cells in the stability, the body of the epidemic prevention and immune response, disease or poisoning cause cell damage and aging, the progress of tumor play an important role, and has potential therapeutic significance.


conception
Cell necrosis is an extreme form of physical, chemical, or severe pathological stimulation that causes cell damage and death.


Long cell death is thought to be caused by pathological passive death, but recent studies have shown that cells necrosis could be programmed to "death" of another kind of form, has the important physiological functions, including trigger inflammation.
When cell apoptosis does not occur normally and the cell must die, necrosis is used as a "substitute" for apoptosis.


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