The division of cells is the most critical mechanism of biological life. Twenty years ago, scientists discovered that bacteria could split into two daughter cells by forming a Z-ring at the center, but they have not been aware of the specific cell division mechanism.
Researchers from Harvard University, etc., have succeeded in unlocking the puzzle by discovering how bacteria do this: they seem to be able to use bricklayers in more than 25 minutes, "Build a new cell wall from the outside. It is unexpected that these "bricks" will move along the inside of the cell wall under the guidance of the treadmill, and the cell wall is constructed from the support structure that moves forward in the front, followed by a continuous detachment. The results of this study were published in the February 17 issue of the journal Science.
The study was done by advanced microscopic completion, which required the addition of color labels to the cell walls, which were observed by a change in color of the building material only a few seconds at a time. The researchers observed that this was not a continuous process, The process that takes place in different locations. The engine is FtsZ, which builds an arched polymer, moving through a phenomenon called "treadmill", named after the old treadmill of the Middle Ages.
"Using this treadmot, researchers can add some material at the front end to build the move and remove them from the back," explains author Cees Dekker of Delft Polytechnic University in the Netherlands, and our research shows that cells are also used This phenomenon is to build cell walls.
This cell wall is constructed with the help of many collaborative proteins, where FtsZ is the most important part.
"Our new discovery solves the puzzle of how FtsZ coordinates cell division for 25 years, and this protein is like a scaffolding support that takes place on it, but it is not rolling Scaffolding, but constantly refurbished their own fixed scaffolding: cells have been in the process of building a cell wall to form a new scaffolding. Constitute the cell wall of the construction machinery by scaffolding regulation, so follow the speed of the latter if the cells at the same time there are several different Scaffolding, then 10-15 points of porridge will be able to build cell walls, while other proteins also play a role in ensuring that DNA is correctly divided into two parts, as well as the cell membrane is properly closed, etc. The whole process of cell division is very fascinating.
By understanding the entire division of bacterial cells, we can bring new opportunities for the development of new antibiotics, the future we also need to master the knowledge of more bacteria in order to create more weapons against a variety of diseases.
When cells divide, the chromosomes containing our genetic information are separated into two new daughter cells. In the process if there is an error, it may lead to disease. Scientists have created an artificial chromosome in the laboratory to study how cells are self-renewing - a process known as cell division. The method allows researchers to study the key factors involved in cell division, including the formation of many chromosomal structures of proteins, and to help coordinate the DNA fragments of this process.
Researchers from the University of Edinburgh recently found that the cell division process would build a protective barrier that would protect the filaments from other parts of the chromosome and prevent pathogenic errors.
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