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Alternative name
C Krox, DKFZp686G01254, hcKrox, THPOK, ZBTB15, ZBTB7B, Zfp 67, ZFP67, Zinc finger protein 67 homolog, Zinc finger protein Th POK, ZNF857B antibody
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Catalog
A009598
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IP
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PurificationImmunogen affinity purified
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Immunogenzinc finger and BTB domain containing 7B
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Western Blothuman skin tissue were subjected to SDS PAGE followed by western blot withA009598(ZBTB7B antibody) at dilution of 1:400
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Recommended dilutionWB:1:200-1:2000;IF:1:10-1:100;IP:1:200-1:1000
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Product Description specificalTranscription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity).
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Gene nameZBTB7B
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locationNucleus
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Uniprot IDO15156
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Calculated M.W.58kDa
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Observed M.W.58kd
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