Asprosin: the discovery of the new glucose control hormone


2017-08-17 22:20:20 GMT+0800

When the body sends out a lack of nutrition, the liver releases the liver sugar into the circulatory system and plays a vital role in maintaining normal functioning of the body, especially the brain function.
The glucose level in the body is controlled by a series of hormones. When the glucose level fluctuates and the steady state is broken, it causes the body's disease and causes serious consequences.
Researchers from baylor college of medicine in Houston have recently discovered a new type of hormone called Asprosin that promotes the generation and release of glucose.


The Asprosin hormone, secreted by white adipose tissue, is the product of the c-end fracture of the precursor protein precursor, which is released and transported to the liver, according to the study published in the journal Cells.
It binds to the surface receptors of the liver cells, opens the signaling pathway, releases the second messenger cAMP, and causes the islet beta cells to secrete insulin, which ultimately lowers blood sugar.
Based on the discovery of this signaling pathway, researchers can finally achieve the goal of adjusting the insulin level of the patient to the normal level by controlling the combination of Asprosin.
The model is to neutralize Asprosin by using a special antibody which can capture Asprosin, to reduce the amount of Asprosin to the liver cells, inhibit the production of liver sugar, and regulate the insulin level.



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